A new study conducted by researchers at the University of Connecticut has revealed a correlation between the prevalence of particular clades of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the growth rate of the associated illness coronavirus disease 2019 (COVID-19).
Researchers found that models of early COVID-19 growth dynamics that included the different clades the virus has mutated into significantly improved growth rate predictions.
Including clades in the models was also more important than incorporating the SARS-CoV-2 variant D614G, which has been associated with increased viral load and infectivity.
More specifically, a higher prevalence of the clades 19A and 19B, which emerged during the Wuhan outbreak, correlated with lower growth rates. Higher prevalence of the clades 20A and 20C, which emerged from 19A and was prominent early on in the European outbreak, correlated with higher growth rates.
The researchers say that without intervention, COVID-19 has the potential to grow more quickly in regions dominated by the 20A and 20C clades, which includes most of South and North America.
Original study can be found on the medRxiv server and is currently under peer review: https://www.medrxiv.org/content/10.1101/2020.09.29.20202416v1
Vaccination rates vary by county, determined by local factors
COVID-19 has disproportionately affected certain underserved and high-risk populations, including people of color, those with underlying health conditions, and those who are socioeconomically disadvantaged. Ensuring access to COVID-19 vaccines for these communities can help address the disparate health effects of the virus and achieve herd immunity.
The Biden administration has identified vaccine equity as a priority, but states and local jurisdictions vary in how and the extent to which they prioritize equity. Given that vaccine roll-out in the U.S. is inherently local, understanding how vaccination rates vary at the local level is important for informing outreach efforts and addressing equity.
Earlier CDC analysis found that, as of early March, counties with high social vulnerability had lower vaccination rates than counties with low social vulnerability.
Source: Kaisesr Permanente Foundation
Dr. Anandi Gopal Joshi, the first Indian physician trained in the United States
Anandibai travelled to New York from Kolkata (Calcutta) by ship, chaperoned by two female English missionary acquaintances of the Thorborns. In New York, Theodicia Carpenter received her in June 1883. Anandibai wrote to the Woman’s Medical College of Pennsylvania in Philadelphia, asking to be admitted to their medical program, which was the second women’s medical […]